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New neurological symptoms : Numbness, weakness, loss of sensation, or difficulty walking may indicate peripheral neuropathy or other neurological conditions requiring investigation

At the receptor level, cagrilintide is a non-selective agonist of the calcitonin receptor (CTR) and amylin receptors (AMYRs)

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Exercise is a compelling domain in which to probe the broader effects of GLP-1R agonists, as it engages reward and motivation systems while serving as a major contributor to energy balance and overall physical and mental health (Ding et al., 2025